Knockout of the DAS gene increases S-adenosylmethionine production in Komagataella phaffii
S-adenosylmethionine (SAM) is an important compound in living organisms and has a number of different roles, such as polyamine synthesis.It can also be used for the treatment of diseases.Gene targeting with homologous recombination in Komagataella phaffii (K.phaffii) created DAS1 and DAS2 gene knockout strains, which use the methanol pathway to gen